Synthetic single-framework antibody library integrated with rapid affinity maturation by VL shuffling-Reference-Cited by-同舟云学术

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Synthetic single-framework antibody library integrated with rapid affinity maturation by VL shuffling

Published:2011-06-16 Issue:9 Volume:24 Page:691-700
ISSN:1741-0126
Container-title:Protein Engineering Design and Selection
language:en
Short-container-title:Protein Engineering Design and Selection

Author:

Brockmann E.- C.,Akter S.,Savukoski T.,Huovinen T.,Lehmusvuori A.,Leivo J.,Saavalainen O.,Azhayev A.,Lovgren T.,Hellman J.,Lamminmaki U.

Publisher

Oxford University Press (OUP)

Subject

Molecular Biology,Biochemistry,Bioengineering,Biotechnology

Link

http://academic.oup.com/peds/article-pdf/24/9/691/4438990/gzr023.pdf

Reference53 articles.

1. Factors Influencing the Dimer to Monomer Transition of an Antibody Single-Chain Fv Fragment

2. A Human Synthetic Combinatorial Library of Arrayable Single-chain Antibodies based on Shuffling in Vivo Formed CDRs into General Framework Regions

3. The use of native T7 DNA polymerase for site-directed mutagenesis

4. Selecting for antibody scFv fragments with improved stability using phage display with denaturation under reducing conditions

5. Neutralizing Human Anti Crotoxin scFv Isolated from a Nonimmunized Phage Library

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