Origin of stereoselectivity in an isothiourea catalyzed Michael addition reaction of aryl ester with vinyl disulfone

Author:

Wang Congcong12345ORCID,Li Shi-Jun6578ORCID,Zhang Min6578,Wei Donghui6578ORCID,Ding Lina12345ORCID

Affiliation:

1. Collaborative Innovation Center of New Drug Research and Safety Evaluation, Henan Province

2. Key Laboratory of Technology of Drug Preparation (Zhengzhou University)

3. Ministry of Education of China

4. Key Laboratory of Henan Province for Drug Quality and Evaluation, School of Pharmaceutical Sciences

5. Zhengzhou University

6. College of Chemistry, and Institute of Green Catalysis

7. Zhengzhou 450001

8. P. R. China

Abstract

The origin of stereoselectivity in an isothiourea-catalyzed addition reaction of aryl ester with vinyl disulfone was explored for the first time.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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