Integrated experimental and computational approach to understand the effects of heavy ion radiation on skin homeostasis

Author:

von Neubeck Claere12,Shankaran Harish3,Geniza Matthew J.4,Kauer Paula M.5,Robinson R. Joe5,Chrisler William B.5,Sowa Marianne B.5

Affiliation:

1. German Cancer Consortium (DKTK), OncoRay - National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany

2. German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany

3. Computational Biology and Bioinformatics, Pacific Northwest National Laboratory, Richland, WA, USA

4. Molecular and Cellular Biology Program, Oregon State University, Corvallis, OR, USA

5. Systems Toxicology, Pacific Northwest National Laboratory, P.O. Box 999, MS J4-02, Richland, WA 99352, USA. Fax: +1 509-371-7304; Tel: +1 509-371-6898

Publisher

Oxford University Press (OUP)

Subject

Biochemistry,Biophysics

Reference59 articles.

1. Hallmarks of cancer: the next generation;Hanahan;Cell,2011

2. Apoptosis in skin cancer development and regression;Batinac;Coll. Antropol.,2007

3. It takes a tissue to make a tumor: epigenetics, cancer and the microenvironment;Barcellos-Hoff;J. Mammary Gland Biol. Neoplasia,2001

4. Radiation and the microenvironment – tumorigenesis and therapy;Barcellos-Hoff;Nat. Rev. Cancer,2005

5. Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm);Curren;Mutat. Res.,2006

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