A new synthetic route towards multifunctionalized cyclic amidrazones for feeding chemical space-Reference-Cited by-同舟云学术

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A new synthetic route towards multifunctionalized cyclic amidrazones for feeding chemical space

Published:2024 Issue:12 Volume:22 Page:2404-2408
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Leblanc Johann¹,Boutin Margaux¹,Vega Clara¹^ORCID,Mathé-Allainmat Monique¹,Grosse Sandrine²,Guillemont Jérôme³,Lebreton Jacques¹,Tessier Arnaud¹^ORCID

Affiliation:

1. Nantes Université, CNRS, CEISAM, UMR 6230, 2 rue de la Houssinière, BP 92208, F-44000 Nantes, France

2. Janssen Research & Development, Turnhoutseweg 30, 2340 Beerse, Belgium

3. NovAliX on-site Janssen-Cilag, Centre de recherche Pharma, Campus de Maigremont BP615, F-27106 Val de Reuil Cedex, France

Abstract

Our molecular landscape can now take into account new 3D-building blocks: multifunctionalized cyclic amidrazones.

Funder

Janssen Pharmaceuticals

Centre National de la Recherche Scientifique

Université de Nantes

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D3OB02092D

Reference29 articles.

1. The importance of synthetic chemistry in the pharmaceutical industry

2. A Medicinal Chemist’s Guide to Molecular Interactions

3. The Influence of Bioisosteres in Drug Design: Tactical Applications to Address Developability Problems

4. Rings in Clinical Trials and Drugs: Present and Future

5. Trends in small molecule drug properties: A developability molecule assessment perspective

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