Magneto-mechanical destruction of cancer-associated fibroblasts using ultra-small iron oxide nanoparticles and low frequency rotating magnetic fields

Author:

Lopez Sara12,Hallali Nicolas1,Lalatonne Yoann34ORCID,Hillion Arnaud1,Antunes Joana C.3,Serhan Nizar12,Clerc Pascal12,Fourmy Daniel12,Motte Laurence3,Carrey Julian1,Gigoux Véronique12ORCID

Affiliation:

1. Laboratoire de Physique et Chimie des Nano-Objets (LPCNO), CNRS-UPS-INSA UMR5215, 135 Avenue de Rangueil, F-31077 Toulouse, France

2. INSERM ERL1226, Receptology and Targeted Therapy of Cancers, 1 Avenue du Professeur Jean Poulhes, F-31432 Toulouse, France

3. Université Sorbonne Paris Nord, Laboratory for Vascular Translational Science, LVTS, INSERM, UMR 1148, F-93000 Bobigny, France

4. Services de Biochimie et Médecine Nucléaire, Hôpital Avicenne Assistance Publique-Hôpitaux de Paris, F-93009 Bobigny, France

Abstract

The destruction of cells using the mechanical activation of magnetic nanoparticles with low-frequency magnetic fields opens new opportunities for cancer treatment.

Funder

Ligue Contre le Cancer

Cancéropôle Grand Ouest

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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