Bioavailability and biotransformation of linolenic acid from basil seed oil as a novel source of omega-3 fatty acids tested on a rat experimental model

Author:

Martínez Rosario12ORCID,Mesas Cristina34,Guzmán Ana13,Galisteo Milagros5,López-Jurado María2,Prados José346,Melguizo Consolación346,Bermúdez Francisco1,Porres Jesus M.2ORCID

Affiliation:

1. Cellbitec S.L., N.I.F. B04847216, Scientific Headquarters of the Almería Technology Park, Universidad de Almería, 04128 La Cañada, Almería, Spain

2. Department of Physiology, Institute of Nutrition and Food Technology (INyTA), Biomedical Research Center (CIBM), Universidad de Granada, 18100 Granada, Spain

3. Institute of Biopathology and Regenerative Medicine (IBIMER), Biomedical Research Center (CIBM), University of Granada, 18100 Granada, Spain

4. Department of Anatomy and Embryology, Faculty of Medicine, University of Granada, 18071 Granada, Spain

5. Department of Pharmacology, School of Pharmacy, University of Granada, 18071 Granada, Spain

6. Instituto Biosanitario de Granada (ibs. GRANADA), 18014 Granada, Spain

Abstract

Basil seed oil is a good source of α-linolenic acid that did not induce adverse effects in vivo, exhibiting high bioaccessibility, increased ALA, and decreased content of pro-inflammatory precursor arachidonic acid in plasma, liver and erythrocytes.

Funder

Ministerio de Ciencia e Innovación

Junta de Andalucía

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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