Synthesis, biological evaluation and X-ray crystallographic studies of imidazo[1,2-a]pyridine-based Mycobacterium tuberculosis glutamine synthetase inhibitors-Reference-Cited by-同舟云学术

Synthesis, biological evaluation and X-ray crystallographic studies of imidazo[1,2-a]pyridine-based Mycobacterium tuberculosis glutamine synthetase inhibitors

Published:2012 Issue:5 Volume:3 Page:620
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Nordqvist Anneli,Nilsson Mikael T.,Lagerlund Olof,Muthas Daniel,Gising Johan,Yahiaoui Samir,Odell Luke R.,Srinivasa Bachally R.,Larhed Mats,Mowbray Sherry L.,Karlén Anders

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2012/MD/C2MD00310D

Reference32 articles.

1. XDR Tuberculosis — Implications for Global Public Health

2. Glutamine synthetase of Mycobacterium tuberculosis: extracellular release and characterization of its enzymatic activity.

3. Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery

4. An Inhibitor of Exported Mycobacterium tuberculosis Glutamine Synthetase Selectively Blocks the Growth of Pathogenic Mycobacteria in Axenic Culture and in Human Monocytes: Extracellular Proteins as Potential Novel Drug Targets

5. Inhibition of Mycobacterium tuberculosis Glutamine Synthetase as a Novel Antibiotic Strategy against Tuberculosis: Demonstration of Efficacy In Vivo

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