Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery-Reference-Cited by-同舟云学术

Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery

Published:2008-05 Issue:10 Volume:16 Page:5501-5513
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Nordqvist Anneli,Nilsson Mikael T.,Röttger Svenja,Odell Luke R.,Krajewski Wojciech W.,Evalena Andersson C.,Larhed Mats,Mowbray Sherry L.,Karlén Anders

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference79 articles.

1. The Need for New Drugs against Tuberculosis

2. Progress in TB drug development and what is still needed

3. Structural model for the reaction mechanism of glutamine synthetase, based on five crystal structures of enzyme-substrate complexes

4. Glutamine synthetase of Mycobacterium tuberculosis: extracellular release and characterization of its enzymatic activity.

5. Genes required for mycobacterial growth defined by high density mutagenesis

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