Characterization of a carboxyl methyltransferase in Fusarium graminearum provides insights into the biosynthesis of fusarin A

Author:

Yang Qian12345ORCID,Wang Wanqiu67895,Lin Yueting1011121314,Lin Yuqi12345,Tang Zhijun12345ORCID,Wang Jing12345,Tao Jiang1011121314,Tang Weihua67895,Liu Wen12345ORCID

Affiliation:

1. State Key Laboratory of Bioorganic and Natural Products Chemistry

2. Center for Excellence in Molecular Synthesis

3. Shanghai Institute of Organic Chemistry

4. University of Chinese Academy of Sciences

5. Shanghai 200032

6. National Key Laboratory of Plant Molecular Genetics

7. CAS Center for Excellence in Molecular Plant Sciences

8. Institute of Plant Physiology and Ecology

9. Chinese Academy of Sciences

10. Department of General Dentistry

11. Ninth People's Hospital

12. Shanghai Jiao Tong University School of Medicine

13. Shanghai 200011

14. China

Abstract

We report here an S-adenosyl methionine-dependent carboxyl methyltransferase responsible for the formation of the methyl ester moiety by biochemical characterization, which provide insights into the biosynthetic pathway of fusarin A.

Funder

National Key Research and Development Program of China

Chinese Academy of Sciences

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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