Affiliation:
1. Eidgenössische Technische Hochschule (ETH), Zürich, Switzerland
Abstract
Shotgun metagenomic approaches to uncover new enzymes are underdeveloped relative to PCR- or activity-based functional metagenomics. Here we review computational and experimental strategies to discover biosynthetic enzymes from metagenomes.
Funder
Gordon and Betty Moore Foundation
Promedica Stiftung
Eidgenössische Technische Hochschule Zürich
ETH Zürich Foundation
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Helmut Horten Stiftung
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
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