Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions

Author:

Dziuba Dmytro12345ORCID,Pospíšil Petr6275,Matyašovský Ján12345,Brynda Jiří12345,Nachtigallová Dana12345,Rulíšek Lubomír12345,Pohl Radek12345,Hof Martin6275,Hocek Michal12345ORCID

Affiliation:

1. Institute of Organic Chemistry and Biochemistry

2. Czech Academy of Sciences

3. Gilead & IOCB Research Center

4. CZ-16610 Prague 6

5. Czech Republic

6. J. H eyrovský Institute of Physical Chemistry

7. CZ-182 23 Prague

Abstract

Color-changing fluorescent nucleotide and oligonucleotide probes for studying interactions with other biomolecules were designed and prepared, and perform better than currently known environment-sensitive fluorophores.

Funder

Czech Science Foundation

Akademie ved Ceské Republiky

Gilead Sciences

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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