Bioactive spiropyrrolizidine oxindole alkaloid enantiomers from Isatis indigotica Fortune-Reference-Cited by-同舟云学术

Bioactive spiropyrrolizidine oxindole alkaloid enantiomers from Isatis indigotica Fortune

Published:2018 Issue:48 Volume:16 Page:9430-9439
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Liu Si-Fan¹²³⁴⁵,Lin Bin⁶⁴⁷,Xi Yu-Fei¹²³⁴⁵,Zhou Le¹²³⁴⁵,Lou Li-Li¹²³⁴⁵,Huang Xiao-Xiao¹²³⁴⁵^ORCID,Wang Xiao-Bo⁸⁹¹⁰,Song Shao-Jiang¹²³⁴⁵^ORCID

Affiliation:

1. School of Traditional Chinese Materia Medica

2. Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development

3. Liaoning Province

4. Shenyang Pharmaceutical University

5. Shenyang 110016

6. School of Pharmaceutical Engineering

7. China

8. Chinese People's Liberation Army 210 Hospital

9. Dalian 116021

10. People's Republic of China

Abstract

Four pairs of new alkaloids, isatindigotindoline A–D, were isolated from Isatis indigotica, and were evaluated for their anti-Aβ1–42 aggregation effects.

Funder

China Postdoctoral Science Foundation

Department of Education of Liaoning Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB02046A

Reference21 articles.

1. Two pairs of unusual scalemic enantiomers from Isatis indigotica leaves

2. Phenylpropanoids and some nitrogen-containing constituents from the roots of Isatis indigotica Fort. (Cruciferae)

3. Enantiomers of an Indole Alkaloid Containing Unusual Dihydrothiopyran and 1,2,4-Thiadiazole Rings from the Root of Isatis indigotica

4. Isatisine A, a Novel Alkaloid with an Unprecedented Skeleton from Leaves of Isatis indigotica

5. New alkaloids from Isatis indigotica

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