<i>N</i>-1,2,3-Triazole–isatin derivatives: anti-proliferation effects and target identification in solid tumour cell lines-Reference-Cited by-同舟云学术

N-1,2,3-Triazole–isatin derivatives: anti-proliferation effects and target identification in solid tumour cell lines

Published:2022 Issue:8 Volume:13 Page:970-977
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Busto Natalia¹^ORCID,Leitão-Castro Joana²,García-Sosa Alfonso T.³^ORCID,Cadete Francisco²,Marques Carolina S.⁴^ORCID,Freitas Renata²,Burke Anthony J.⁴⁵^ORCID

Affiliation:

1. Departamento de Ciencias de la Salud, Facultad de Ciencias de la Salud, Universidad de Burgos, Paseo de los Comendadores, s/n, 09001 Burgos, Spain

2. I3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal

3. Institute of Chemistry, University of Tartu, Ravila 14A, Tartu 50411, Estonia

4. LAQV-REQUIMTE, Institute for Research and Advanced Studies, University of Évora, Rua Romão Ramalho, 59, 7000-671 Évora, Portugal

5. Chemistry and Biochemistry Department, School of Science and Technology, University of Évora, Rua Romão Ramalho 59, 7000-671 Évora, Portugal

Abstract

Molecular hybridization approaches have become an important strategy in medicinal chemistry, we have developed a series of novel N-1,2,3-triazole–isatin hybrids that are promising anti-proliferation agents for lung, colon and breast tumours.

Funder

Consejería de Educación, Junta de Castilla y León

Estonian Research Competency Council

Ministerio de Ciencia, Innovación y Universidades

“la Caixa” Foundation

Fundação para a Ciência e a Tecnologia

Ministério da Ciência, Tecnologia e Ensino Superior

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

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