A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications-Reference-Cited by-同舟云学术

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A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications

Published:2017 Issue:3 Volume:17 Page:511-520
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Phan Duc T. T.¹²³⁴^ORCID,Wang Xiaolin⁵⁶⁷⁸,Craver Brianna M.¹²³⁴,Sobrino Agua¹²³⁴,Zhao Da⁹²³⁴,Chen Jerry C.¹²³⁴,Lee Lilian Y. N.¹²³⁴,George Steven C.⁹¹⁰⁴,Lee Abraham P.⁹²³⁴¹¹,Hughes Christopher C. W.¹²³⁴⁹

Affiliation:

1. Department of Molecular Biology & Biochemistry

2. University of California

3. Irvine

4. USA

5. Department of Micro/Nano Electronics

6. Shanghai Jiao Tong University

7. Shanghai

8. China

9. Department of Biomedical Engineering

10. Washington University in St. Louis

11. Department of Mechanical and Aerospace Engineering

Abstract

A vascularized, perfused organ-on-a-chip platform suitable for large-scale drug efficacy/toxicity screening.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2017/LC/C6LC01422D

Reference20 articles.

1. Phase II and Phase III attrition rates 2011–2012

2. Organs-on-chips (microphysiological systems): tools to expedite efficacy and toxicity testing in human tissue

3. Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor

4. Modular, pumpless body-on-a-chip platform for the co-culture of GI tract epithelium and 3D primary liver tissue

5. Reconstituting Organ-Level Lung Functions on a Chip

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