All-purpose nanostrategy based on dose deposition enhancement, cell cycle arrest, DNA damage, and ROS production as prostate cancer radiosensitizer for potential clinical translation-Reference-Cited by-同舟云学术

All-purpose nanostrategy based on dose deposition enhancement, cell cycle arrest, DNA damage, and ROS production as prostate cancer radiosensitizer for potential clinical translation

Published:2021 Issue:34 Volume:13 Page:14525-14537
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Guo Xiao-xiao¹²,Guo Zhen-hu³^ORCID,Lu Jing-song³^ORCID,Xie Wen-sheng³^ORCID,Zhong Qiu-zi⁴,Sun Xiao-dan³,Wang Xiu-mei³^ORCID,Wang Jian-ye¹,Liu Ming¹,Zhao Ling-yun³^ORCID

Affiliation:

1. Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China

2. Graduate School of Peking Union Medical College, Beijing, 100730, China

3. Key Laboratory of Advanced Materials, Ministry of Education of China, School of Materials Science and Engineering, Tsinghua University, Beijing, 100084, China

4. Department of Radiotherapy, National Center of Gerontology, Institute of Geriatric Medicine, Beijing Hospital, Chinese Academy of Medical Science, Beijing, 100730, China

Abstract

A prostate cancer-targeted “all-purpose” radiosensitive nanostrategy based on dose deposition enhancement, G2/M phase arrest, DNA damage, and ROS production, can provides effective radiosensitive efficiency and has high potential for clinical translation.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D1NR03869A

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3. Urinary Incontinence and Erectile Dysfunction After Robotic Versus Open Radical Prostatectomy: A Prospective, Controlled, Nonrandomised Trial