Selective synthesis of trisubstituted (trifluoromethyl)alkenes via ligand-free Cu-catalyzed syn hydroarylation, hydroalkenylation and hydroallylation of (trifluoromethyl)alkynes-Reference-Cited by-同舟云学术

Selective synthesis of trisubstituted (trifluoromethyl)alkenes via ligand-free Cu-catalyzed syn hydroarylation, hydroalkenylation and hydroallylation of (trifluoromethyl)alkynes

Published:2016 Issue:17 Volume:18 Page:4628-4632
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Yamamoto Y.¹²³⁴⁵,Ohkubo E.¹²³⁴⁵,Shibuya M.¹²³⁴⁵

Affiliation:

1. Department of Basic Medicinal Sciences

2. Graduate School of Pharmaceutical Sciences

3. Nagoya University

4. Nagoya 464-8601

5. Japan

Abstract

The Cu-catalyzed hydroarylation, hydroalkenylation, and hydroallylation of (trifluoromethyl)alkynes with organoboron reagents produced diverse (trifluoromethyl)alkenes.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/GC/C6GC01782G

Reference48 articles.

1. Fluorine in Medicinal Chemistry

2. Fluorine in Pharmaceuticals: Looking Beyond Intuition

3. Fluorine in medicinal chemistry

4. The Many Roles for Fluorine in Medicinal Chemistry

5. Breast cancer: Aromatase inhibitors take on tamoxifen

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