Structural changes and picosecond to second dynamics of cytochrome c in interaction with nitric oxide in ferrous and ferric redox states
Author:
Affiliation:
1. Laboratoire Jean Perrin
2. Sorbonne Universités
3. UPMC Univ. Paris 06
4. CNRS
5. 75005 Paris
6. Laboratoire d'Optique et Biosciences
7. INSERM
8. Ecole Polytechnique
9. 91128 Palaiseau
10. France
Abstract
After dissociation NO rebinds to Cyt c in 10 ps whereas Met80 rebinds in 5 μs after NO release from Cyt c. A complete view of heme – NO dynamics within 12 orders of magnitude of time in Cyt c is presented.
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2017/CP/C7CP02634J
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4. Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3
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