Salvianolic acid B prevents body weight gain and regulates gut microbiota and LPS/TLR4 signaling pathway in high-fat diet-induced obese mice-Reference-Cited by-同舟云学术

Salvianolic acid B prevents body weight gain and regulates gut microbiota and LPS/TLR4 signaling pathway in high-fat diet-induced obese mice

Published:2020 Issue:10 Volume:11 Page:8743-8756
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Li Lin¹²³⁴⁵,Li Rui¹²³⁴⁵,Zhu Ruyuan¹²³⁴⁵,Chen Beibei¹²³⁴⁵,Tian Yimiao¹²³⁴⁵,Zhang Hao¹²³⁴⁵,Xia Bingke¹²³⁴⁵,Jia Qiangqiang¹²³⁴⁵,Wang Lili¹²³⁴⁵,Zhao Dandan¹²³⁴⁵,Mo Fangfang¹²³⁴⁵,Li Yu⁶²³⁴⁵,Zhang Shujing⁷²³⁴⁵^ORCID,Gao Sihua¹²³⁴⁵,Zhang Dongwei¹²³⁴⁵^ORCID,Guo Shuzhen⁷²³⁴⁵

Affiliation:

1. Diabetes Research Centre

2. Traditional Chinese Medicine School

3. Beijing University of Chinese Medicine

4. Beijing 100029

5. China

6. Department of Histoembryology

7. The Scientific Research Centre

Abstract

Salvianolic acid B prevents body weight gain and improves insulin sensitivity in obese mice. The underlying mechanism behind these effects may be associated with the regulation of metabolic endotoxemia, gut microbiota homeostasis and LPS/TLR4 pathway.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/FO/D0FO01116A

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