Peptidic β-sheets induce Congo red-derived fluorescence to improve the sensitivity of HIV-1 p24 detection-Reference-Cited by-同舟云学术

Peptidic β-sheets induce Congo red-derived fluorescence to improve the sensitivity of HIV-1 p24 detection

Published:2017 Issue:7 Volume:9 Page:1185-1189
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Sun Hongyan¹²³⁴⁵,Liu Ye⁶⁷⁸⁹¹⁰,Zhang Cuntong¹²³⁴⁵,Luo Xuegang¹²³⁴⁵,Jiang Xingyu⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. Key Laboratory of Industrial Fermentation Microbiology of the Ministry of Education

2. Tianjin Key Laboratory of Industrial Microbiology College of Biotechnology

3. Tianjin University of Science and Technology

4. Tianjin 300457

5. China

6. Beijing Engineering Research Center for BioNanotechnology

7. CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety

8. CAS Center for Excellence in Nanoscience

9. National Center for NanoScience and Technology

10. Beijing 100190

Abstract

We employ a peptide which contains a 2-phenylalanine core component to efficiently form β-sheets, which can combine with Congo red molecules and produce strong fluorescence with high sensitivity to ensure an earlier diagnosis of HIV infection.

Funder

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/AY/C6AY03489F

Reference25 articles.

1. In situ formation of peptidic nanofibers can fundamentally optimize the quality of immune responses against HIV vaccine

2. Polyvinylpyrrolidone–Poly(ethylene glycol) Modified Silver Nanorods Can Be a Safe, Noncarrier Adjuvant for HIV Vaccine

3. A Peptide-Based Nanofibrous Hydrogel as a Promising DNA Nanovector for Optimizing the Efficacy of HIV Vaccine

4. Advances in biosensing strategies for HIV-1 detection, diagnosis, and therapeutic monitoring

5. Promotion of rapid testing for HIV in primary care (RHIVA2): a cluster-randomised controlled trial

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