In situ formation of peptidic nanofibers can fundamentally optimize the quality of immune responses against HIV vaccine-Reference-Cited by-同舟云学术

In situ formation of peptidic nanofibers can fundamentally optimize the quality of immune responses against HIV vaccine

Published:2016 Issue:2 Volume:1 Page:135-143
ISSN:2055-6756
Container-title:Nanoscale Horizons
language:en
Short-container-title:Nanoscale Horiz.

Author:

Liu Ye¹²³⁴,Wang Huaimin⁵⁶⁷⁸⁹,Li Dan¹⁰¹¹¹²¹³⁴,Tian Yue¹²³⁴,Liu Wenwen¹²³⁴,Zhang Lingmin¹²³⁴,Zheng Wenshu¹²³⁴,Hao Yanling¹⁰¹¹¹²¹³⁴,Liu Jiandong¹⁰¹¹¹²¹³⁴,Yang Zhimou⁵⁶⁷⁸⁹,Shao Yiming¹⁰¹¹¹²¹³⁴,Jiang Xingyu¹²³⁴

Affiliation:

1. Beijing Engineering Research Center for BioNanotechnology and CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety

2. National Center for NanoScience and Technology

3. Beijing 100190

4. China

5. State Key Laboratory of Medicinal Chemical Biology

6. Key Laboratory of Bioactive Materials

7. Ministry of Education, and College of Life Sciences, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)

8. Nankai University

9. Tianjin 300071

10. State Key Laboratory of Infectious Disease Prevention and Control

11. National Center for AIDS/STD Control and Prevention

12. Chinese Center for Disease Control and Prevention

13. Beijing

Abstract

Peptidic nanofibers can provide convenience for administration, and facilitate the induction of multiple crucial immunities against HIV DNA vaccine, including polyfunctional T cell response, broad IgG subclasses response, and V1/V2 loop-specific antibody response.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2016/NH/C5NH00064E

Reference32 articles.

1. Immunologic strategies for HIV-1 remission and eradication

2. The immune response during acute HIV-1 infection: clues for vaccine development

3. The Ability of an Oligomeric Human Immunodeficiency Virus Type 1 (HIV-1) Envelope Antigen To Elicit Neutralizing Antibodies against Primary HIV-1 Isolates Is Improved following Partial Deletion of the Second Hypervariable Region

4. Enhancing SIV-specific immunity in vivo by PD-1 blockade

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