Tetrazolone as an acid bioisostere: application to marketed drugs containing a carboxylic acid
Author:
Affiliation:
1. Rigel Pharmaceuticals
2. Inc.
3. South San Francisco
4. USA
Abstract
Matched molecular pair analysis was used to evaluate the ability of a tetrazolone group to act as a bioisostere of a carboxylic acid.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01646D
Reference29 articles.
1. Properties of Known Drugs. 2. Side Chains
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