Selective detection of phospholipids in human blood plasma and single cells for cancer differentiation using dispersed solid-phase microextraction combined with extractive electrospray ionization mass spectrometry

Author:

Zhang Hua12345ORCID,Lu Haiyan56784ORCID,Huang Keke56784ORCID,Li Jiajia9104,Wei Feng11104,Liu Aiying56784,Chingin Konstantin1234,Chen Huanwen12345

Affiliation:

1. Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation

2. East China University of Technology

3. Nanchang 330013

4. P. R. China

5. State Key Laboratory of Inorganic Synthesis and Preparative Chemistry

6. College of Chemistry

7. Jilin University

8. Changchun 130012

9. Department of Obstetrics and Gynecology

10. The First Hospital of Jilin University

11. Department of Hepatobiliary and Pancreatic Surgery

Abstract

Rapid and selective determination of phospholipids in microvolume biofluid samples for cancer differentiation was achieved by d-SPME–iEESI-MS.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

National Basic Research Program of China

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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