Anti-HSV activity and mode of action study of α-pyrone carboxamides
Author:
Affiliation:
1. Department of Applied Chemistry
2. Birla Institute of Technology
3. Ranchi 835215, India
4. ICMR Virus Unit
5. ID & BG Hospital
6. Kolkata 700010, India
Abstract
Potential anti-HSV lead candidate3d(EC50= 9.8 μg ml−1) and its possible binding mode to utilize cavity-A and cavity-B of viral enzyme HSV polymerase.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA01303D
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