Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses

Author:

Brideau Roger J.,Knechtel Mary L.,Huang Audris,Vaillancourt Valerie A.,Vera Ellen E.,Oien Nancee L.,Hopkins Todd A.,Wieber Janet L.,Wilkinson Karen F.,Rush Bob D.,Schwende Francis J.,Wathen Michael W.

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference18 articles.

1. Effect of pyrimidinone treatment on lethal and immunosuppressive murine cytomegalovirus infection;Brideau;Antimicrob. Agents Chemother.,1985

2. Brideau, R.J., Knechtel, M.L., Vaillancourt, V.A., Huang, A., Staley, S.A., Clayton, T.L., Tucker, J.A., Oien, N.L., Wieber, J.L., Hopkins, T.A., Wathen, M.W., 2000. Broad spectrum anti-herpesvirus cell culture activity of novel 4-hydroxyquinolines which target the viral polymerase abs. 40th ICAAC, Toronto, Canada, p. 1856.

3. Resistance of herpesviruses to antiviral drugs;Chatis;Antimicrob. Agents Chemother.,1992

4. Mutation in region III of the DNA polymerase gene conferring foscarnet resistance in cytomegalovirus isolates from subjects receiving prolonged antiviral therapy;Chou;J. Infect. Dis.,1998

5. Human cytomegalovirus DNA polymerase and antiviral drug resistance: recent progress;Cihlar;Int. Antiviral News,1998

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