Direct detection and drug-resistance profiling of bacteremias using inertial microfluidics

Author:

Hou Han Wei1234,Bhattacharyya Roby P.53467,Hung Deborah T.53487,Han Jongyoon12349

Affiliation:

1. Department of Electrical Engineering & Computer Science

2. Massachusetts Institute of Technology

3. Cambridge

4. USA

5. The Broad Institute

6. Division of Infectious Diseases

7. Massachusetts General Hospital

8. Department of Molecular Biology and Center for Computational and Integrative Biology

9. Department of Biological Engineering

Abstract

Isolation of low-abundance bacteria from whole blood for direct pathogen identification and antibiotic susceptibility determination using hybridization-based RNA detection.

Funder

Harvard Catalyst

SPAWAR Systems Center Pacific, Space and Naval Warfare Systems Command

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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