Separation of Activated T Cells Using Multidimensional Double Spiral (MDDS) Inertial Microfluidics for High-Efficiency CAR T Cell Manufacturing-Reference-Cited by-同舟云学术

Separation of Activated T Cells Using Multidimensional Double Spiral (MDDS) Inertial Microfluidics for High-Efficiency CAR T Cell Manufacturing

Published:2024-06-18 Issue:26 Volume:96 Page:10780-10790
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Jeon Hyungkook¹^ORCID,Perez Caleb R.^ORCID,Kyung Taeyoon,Birnbaum Michael E.²³^ORCID,Han Jongyoon²

Affiliation:

1. Department of Manufacturing Systems and Design Engineering (MSDE), Seoul National University of Science and Technology (SEOULTECH), 232 Gongneung-ro, Nowon-gu, Seoul 01811, Republic of Korea

2. Singapore-MIT Alliance for Research and Technology (SMART) Centre, Critical Analytics for Manufacturing Personalized-Medicine (CAMP) IRG, 1 CREATE Way, No. 04-13/14 Enterprise Wing, 138602, Singapore

3. Ragon Institute of Mass General, MIT, and Harvard, 400 Technology Square, Cambridge, Massachusetts 02139, United States

Funder

National Institute for Innovation in Manufacturing Biopharmaceuticals

Singapore-MIT Alliance for Research and Technology Centre

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.4c01981

Reference46 articles.

1. Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia

2. CAR T cell immunotherapy for human cancer

3. Global Manufacturing of CAR T Cell Therapy

4. Mechanisms of resistance to CAR T cell therapy

5. Expamers: a new technology to control T cell activation

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