Global Manufacturing of CAR T Cell Therapy

Author:

Levine Bruce L.,Miskin James,Wonnacott Keith,Keir Christopher

Funder

Novartis Pharmaceuticals

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference62 articles.

1. Expression of chimeric receptor composed of immunoglobulin-derived V regions and T-cell receptor-derived C regions;Kuwana;Biochem. Biophys. Res. Commun.,1987

2. Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity;Gross;Proc. Natl. Acad. Sci. USA,1989

3. Chimeric receptors providing both primary and costimulatory signaling in T cells from a single gene product;Finney;J. Immunol.,1998

4. Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta /CD28 receptor;Maher;Nat. Biotechnol.,2002

5. The basic principles of chimeric antigen receptor design;Sadelain;Cancer Discov.,2013

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