A mild and practical method for deprotection of aryl methyl/benzyl/allyl ethers with HPPh2 and tBuOK-Reference-Cited by-同舟云学术

A mild and practical method for deprotection of aryl methyl/benzyl/allyl ethers with HPPh2 and tBuOK

Published:2021 Issue:35 Volume:19 Page:7633-7640
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Pan Wenjing¹,Li Chenchen¹,Zhu Haoyin¹,Li Fangfang²,Li Tao¹^ORCID,Zhao Wanxiang¹^ORCID

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, China

2. The Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China

Abstract

Aryl methyl/benzyl/allyl ethers with various functional groups reacted smoothly to afford deprotected products in high yields, and further investigation showed that deallylation is easier than debenzylation and demethylation.

Funder

National Natural Science Foundation of China

Thousand Young Talents Program of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01286J

Reference96 articles.

1. The Chemistry of Phenols , ed. Z. Rappoport , Wiley-VCH , Weinheim , 2003