Controlling the pyridinium–zwitterionic ligand ratio on atomically precise gold nanoclusters allowing for eradicating Gram-positive drug-resistant bacteria and retaining biocompatibility-Reference-Cited by-同舟云学术

Controlling the pyridinium–zwitterionic ligand ratio on atomically precise gold nanoclusters allowing for eradicating Gram-positive drug-resistant bacteria and retaining biocompatibility

Published:2021 Issue:44 Volume:12 Page:14871-14882
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Pang Zeyang¹²,Li Qizhen¹,Jia Yuexiao¹,Yan Weixiao¹,Qi Jie¹,Guo Yuan³^ORCID,Hu Fupin⁴,Zhou Dejian²^ORCID,Jiang Xingyu¹^ORCID

Affiliation:

1. Department of Biomedical Engineering, Southern University of Science and Technology, No 1088, Xueyuan Rd, Nanshan District, Shenzhen, Guangdong 518055, P. R. China

2. School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK

3. School of Food Science and Nutrition and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK

4. Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai 200040, P. R. China

Abstract

A NIR-II fluorescent Au25 nanocluster capped with optimal dual functional ligands can effectively aggregate and kill Gram-positive drug-resistant bacteria while maintaining good biocompatibility.

Funder

Biotechnology and Biological Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC03056F

Reference60 articles.

1. Antibacterial discovery and development—the failure of success?

2. The drug-resistant bacteria that pose the greatest health threats

3. The antimicrobial activity of nanoparticles: present situation and prospects for the future