A bioorthogonal approach for imaging the binding between Dasatinib and its target proteins inside living cells-Reference-Cited by-同舟云学术

A bioorthogonal approach for imaging the binding between Dasatinib and its target proteins inside living cells

Published:2016 Issue:79 Volume:52 Page:11764-11767
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Kim Young-Rang¹²³⁴,Kim Young Hye⁵²⁶⁴,Kim Sung Woo¹²³⁴,Lee Yong Ju¹²³⁴,Chae Dong-Eon¹²³⁴⁷,Kim Kyung-A¹²³⁴⁷,Lee Zee-Won⁸⁹⁴,Kim Nam Doo¹⁰¹¹¹²⁴,Choi Jong-Soon¹²³⁴⁷,Choi Insung S.¹³¹⁴¹⁵⁴,Lee Kyung-Bok¹²³⁴

Affiliation:

1. Division of Bioconvergence Analysis

2. Korea Basic Science Institute (KBSI)

3. Daejeon 34133

4. Korea

5. Biomedical Omics Group

6. Cheongju 28119

7. Graduate School of Analytical Science and Technology (GRAST)

8. Drug Discovery System & Pharmaceuticals, Inc. (DDSPharm)

9. Daejeon 34165

10. New Drug Development Center

11. Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF)

12. Daegu 41061

13. Center for Cell-Encapsulation Research and Department of Chemistry

14. Korea Advanced Institute of Science and Technology (KAIST)

15. Daejeon 34141

Abstract

A simple method for reading out the binding between a chemical drug and its target proteins in the cytoplasm is demonstrated.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC07011F

Reference33 articles.

1. Visualization and targeted disruption of protein interactions in living cells

2. Identifying compound efficacy targets in phenotypic drug discovery

3. In Situ Monitoring of Bindings between Dasatinib and Its Target Protein Kinases Using Magnetic Nanoparticles in Live Cells

4. Proteomic profiling and potential cellular target identification of K11777, a clinical cysteine protease inhibitor, in Trypanosoma brucei

5. Parasite‐Based Screening and Proteome Profiling Reveal Orlistat, an FDA‐Approved Drug, as a Potential AntiTrypanosoma bruceiAgent[]

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Clicking in harmony: exploring the bio-orthogonal overlap in click chemistry;RSC Advances;2024

2. In Vivo Applications of Bioorthogonal Reactions: Chemistry and Targeting Mechanisms;Chemistry – A European Journal;2023-03-02

3. From the Huisgen cycloaddition to bioorthogonal chemistry. A commentary on the 2022 Nobel Prize in Chemistry;Anales de la Real Academia Nacional de Farmacia;2022-12-31

4. Self-assembling a natural small molecular inhibitor that shows aggregation-induced emission and potentiates antitumor efficacy;Nanoscale Horizons;2021

5. Biomedical applications of copper-free click chemistry: in vitro, in vivo, and ex vivo;Chemical Science;2019