Biomedical applications of copper-free click chemistry: in vitro, in vivo, and ex vivo-Reference-Cited by-同舟云学术

Biomedical applications of copper-free click chemistry: in vitro, in vivo, and ex vivo

Published:2019 Issue:34 Volume:10 Page:7835-7851
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kim Eunha¹²³⁴^ORCID,Koo Heebeom⁵⁶⁷⁸⁴^ORCID

Affiliation:

1. Department of Molecular Science and Technology

2. Ajou University

3. Suwon 16499

4. Republic of Korea

5. Department of Medical Life Sciences

6. College of Medicine

7. The Catholic University of Korea

8. Seoul

Abstract

Copper-free click chemistry has resulted in a change of paradigm, showing that artificial chemical reactions can occur on cell surfaces, in cell cytosol, or within the body. It has emerged as a valuable tool in biomedical fields.

Funder

Ministry of Science, ICT and Future Planning

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC03368H

Reference103 articles.

1. Click Chemistry: Diverse Chemical Function from a Few Good Reactions

2. Cu-free click cycloaddition reactions in chemical biology

3. Metabolic cross-talk allows labeling of O-linked -N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway

4. Bringing chemistry to life

5. Visualizing biologically active small molecules in cells using click chemistry

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