Enzymatic cyclizations of squalene analogs with threo- and erythro-diols at the 6,7- or 10,11-positions by recombinant squalene cyclase. Trapping of carbocation intermediates and mechanistic insights into the product and substrate specificities-Reference-Cited by-同舟云学术

Enzymatic cyclizations of squalene analogs with threo- and erythro-diols at the 6,7- or 10,11-positions by recombinant squalene cyclase. Trapping of carbocation intermediates and mechanistic insights into the product and substrate specificities

Published:2005 Issue:17 Volume:3 Page:3127
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Abe Takamasa,Hoshino Tsutomu

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2005/OB/B506590A

Reference52 articles.

1. THE CYCLIZATION OF SQUALENE IN CHOLESTEROL SYNTHESIS

2. The Migration and Elimination of Hydrogen during Biosynthesis of Cholesterol from Squalene1

3. Structure and Function of a Squalene Cyclase

4. Conversion of Squalene to the Pentacarbocyclic Hopene

5. Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

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