Pd-Catalysed Suzuki–Miyaura cross-coupling of aryl chlorides at low catalyst loadings in water for the synthesis of industrially important fungicides

Author:

Orecchia Patrizio1,Petkova Desislava Slavcheva2,Goetz Roland2,Rominger Frank3,Hashmi A. Stephen K.13ORCID,Schaub Thomas12ORCID

Affiliation:

1. Catalysis Research Laboratory (CaRLa), Im Neuenheimer Feld 584, 69120 Heidelberg, Germany

2. BASF SE, Carl-Bosch-Str. 38, 67056 Ludwigshafen, Germany

3. Organisch-Chemisches Institut, Heidelberg University, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany

Abstract

The Suzuki–Miyaura coupling reaction of electron-poor aryl chlorides in the synthesis of crop protection-relevant active ingredients in water is disclosed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Reference48 articles.

1. G.Bringmann , C.Günther , M.Ochse , O.Schupp and S.Tasler , in Biaryls in Nature: a Multi-faceted Class of Stereochemically, Progress in the Chemistry of Organic Natural Products , ed. W. Herz , H. Falk , G. W. Kirby and R. E. Moore , Springer , Vienna , 2001 , vol. 82 , pp. 1–249

2. Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds

3. Cross-Coupling Reactions Of Organoboranes: An Easy Way To Construct CC Bonds (Nobel Lecture)

4. From Noble Metal to Nobel Prize: Palladium-Catalyzed Coupling Reactions as Key Methods in Organic Synthesis

5. Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands

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