α-Keto hydrazones in asymmetric aminocatalysis: reactivity through β-amino aza-dienamine intermediates-Reference-Cited by-同舟云学术

α-Keto hydrazones in asymmetric aminocatalysis: reactivity through β-amino aza-dienamine intermediates

Published:2021 Issue:13 Volume:8 Page:3446-3456
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Matador Esteban¹²³^ORCID,Retamosa María de Gracia¹²³^ORCID,Rohal'ová Dominika¹²³^ORCID,Iglesias-Sigüenza Javier¹²³,Merino Pedro⁴⁵³^ORCID,Fernández Rosario¹²³^ORCID,Lassaletta José M.⁶⁷³^ORCID,Monge David¹²³^ORCID

Affiliation:

1. Departamento de Química Orgánica and Centro de Innovación en Química Avanzada (ORFEO-CINQA)

2. 41012 Sevilla

3. Spain

4. Instituto de Biocomputación y Física de Sistemas Complejos (BIFI). Universidad de Zaragoza

5. 50009 Zaragoza

6. Instituto de Investigaciones Químicas (CSIC-US) and Centro de Innovación en Química Avanzada (ORFEO-CINQA)

7. 41092 Sevilla

Abstract

α-keto hydrazones activated by a bifunctional amino-thiourea catalyst generate β-amino aza-dienamine intermediates which react with nitroalkenes in highly enantioselective fashion.

Funder

Gobierno de Aragón

Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía

Ministerio de Ciencia e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00384D

Reference52 articles.

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3. Hydrogen Bonding in Organic Synthesis , ed. P. M. Pihko , Wiley-VCH , Weinheim , 2009

4. Asymmetric Organocatalysis: From Infancy to Adolescence

5. The advent and development of organocatalysis

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