Asymmetric cross-aldol reactions of α-keto hydrazones and α,β-unsaturated γ-keto hydrazones with trifluoromethyl ketones-Reference-Cited by-同舟云学术

Asymmetric cross-aldol reactions of α-keto hydrazones and α,β-unsaturated γ-keto hydrazones with trifluoromethyl ketones

Published:2021 Issue:89 Volume:57 Page:11835-11838
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Alberca Saúl¹^ORCID,Matador Esteban¹^ORCID,Iglesias-Sigüenza Javier¹,de Gracia Retamosa Ma¹²^ORCID,Fernández Rosario¹^ORCID,Lassaletta José M.³^ORCID,Monge David¹^ORCID

Affiliation:

1. Departamento de Química Orgánica, Universidad de Sevilla and Centro de Innovación en Química Avanzada (ORFEO-CINQA), C/Prof. García González, 1, 41012 Sevilla, Spain

2. Departamento de Química Orgánica e Instituto de Síntesis Orgánica, Universidad de Alicante, Centro de Innovación en Química Avanzada (ORFEO-CINQA), 03080-Alicante, Spain

3. Instituto de Investigaciones Químicas (CSIC-US) and Centro de Innovación en Química Avanzada (ORFEO-CINQA), Avda. Américo Vespucio, 49, 41092 Sevilla, Spain

Abstract

Asymmetric cross-aldol reactions of α-keto hydrazones and α,β-unsaturated γ-keto hydrazones with trifluoromethyl ketones afford easy-to-functionalize tertiary trifluoromethyl alcohols with high enantioselectivity.

Funder

Ministerio de Ciencia, Innovación y Universidades

Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CC/D1CC05014A

Reference35 articles.

1. Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

2. Fluorine in medicinal chemistry

3. I.Ojima , Fluorine in Medicinal Chemistry and Chemical Biology , Wiley-Blackwell , Chichester, UK , 2009

4. T.Hiyama , in Organofluorine Compounds: Chemistry and Applications , ed. H. Yamamoto , Springer , New York , 2000

5. Organic fluorine compounds: a great opportunity for enhanced materials properties

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