211At-labeled immunoconjugate via a one-pot three-component double click strategy: practical access to α-emission cancer radiotherapeutics-Reference-Cited by-同舟云学术

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211At-labeled immunoconjugate via a one-pot three-component double click strategy: practical access to α-emission cancer radiotherapeutics

Published:2019 Issue:7 Volume:10 Page:1936-1944
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Fujiki Katsumasa¹²³⁴⁵,Kanayama Yousuke⁶⁷⁸⁴,Yano Shinya⁹¹⁰³⁴,Sato Nozomi⁹¹⁰³⁴,Yokokita Takuya⁹¹⁰³⁴,Ahmadi Peni¹²³⁴,Watanabe Yasuyoshi⁶⁷⁸⁴,Haba Hiromitsu⁹¹⁰³⁴,Tanaka Katsunori¹²³⁴⁵^ORCID

Affiliation:

1. Biofunctional Synthetic Chemistry Laboratory

2. RIKEN Cluster for Pioneering Research

3. Wako

4. Japan

5. GlycoTargeting Research Laboratory

6. Laboratory for Pathophysiological and Health Science

7. RIKEN Center for Biosystems Dynamics Research

8. Kobe

9. Nuclear Chemistry Research Team

10. RIKEN Nishina Center for Accelerator-Based Science

Abstract

A facile synthesis of an ²¹¹At-labeled immunoconjugate for α-emission therapy was achieved based on a one-pot three-component double click method.

Funder

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C8SC04747B

Reference55 articles.

1. Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides

2. The role of coordination chemistry in the development of target-specific radiopharmaceuticals

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