Chemical diversity, medicinal potentialities, biosynthesis, and pharmacokinetics of anthraquinones and their congeners derived from marine fungi: a comprehensive update

Author:

Sebak Mohamed1ORCID,Molham Fatma1,Greco Claudio2ORCID,Tammam Mohamed A.3ORCID,Sobeh Mansour4,El-Demerdash Amr56ORCID

Affiliation:

1. Microbiology and Immunology Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt

2. Molecular Microbiology Department, The John Innes Center, Norwich Research Park, Norwich NR4 7UH, UK

3. Department of Biochemistry, Faculty of Agriculture, Fayoum University, Fayoum 63514, Egypt

4. AgroBioSciences Department, Mohammed VI Polytechnic University (UM6P), Ben Guerir, Morocco

5. Organic Chemistry Division, Department of Chemistry, Faculty of Science, Mansoura University, Mansoura 35516, Egypt

6. Department of Metabolic Biology and Biological Chemistry, The John Innes Center, Norwich Research Park, Norwich NR4 7UH, UK

Abstract

Marine-derived fungi receive excessive attention as prolific producers of structurally unique secondary metabolites. Whilst they are promising substitutes or conjugates for current therapeutics, so far research has only touched on their secondary metabolite diversity.

Funder

Mansoura University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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