Sodium fluoride preserves blood metabolite integrity for biomarker discovery in large-scale, multi-site metabolomics investigations-Reference-Cited by-同舟云学术

Sodium fluoride preserves blood metabolite integrity for biomarker discovery in large-scale, multi-site metabolomics investigations

Published:2024 Issue:4 Volume:149 Page:1238-1249
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Xiong Wenzheng¹²^ORCID,Anthony Daniel C.²,Anthony Suzie³,Ho Thi Bao Tien²^ORCID,Louis Edouard⁴,Satsangi Jack⁵,Radford-Smith Daniel E.¹²^ORCID

Affiliation:

1. Department of Chemistry, University of Oxford, Oxford, UK

2. Department of Pharmacology, Medical Sciences Division, University of Oxford, Oxford, UK

3. Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

4. Department of Gastroenterology, University Hospital CHU of Liège, Liège, Belgium

5. Translational Gastroenterology Unit, Nuffield Department of Experimental Medicine, University of Oxford, Oxford, UK

Abstract

Fluoride oxalate tubes maintained stable glucose and lactate levels in blood for 24 hours, minimizing preanalytical variation. Such tubes offer a viable option for delayed processing in metabolomic studies.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AN/D3AN01359F

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