Affiliation:
1. Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Abstract
Thioamide-based compounds are described as a novel class of metal-binding pharmacophores (MBPs) for developing Zn(ii)-dependent metalloenzyme inhibitors by masking thiol reactivity.
Funder
National Institute of Allergy and Infectious Diseases
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis
Cited by
3 articles.
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