Microwave-assisted palladium-catalysed isonitrile insertion in 2-bromophenylureas for efficient synthesis of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines
Author:
Affiliation:
1. Medicinal & Process Chemistry Division
2. CSIR-Central Drug Research Institute
3. Lucknow-226031
4. India
5. Academy of Scientific and Innovative Research
Abstract
The palladium-catalysed isonitrile insertion in 2-bromophenylureas leads to the formation of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines via C–O cross coupling reaction of the intermediate imidoylpalladium species.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA03062E
Reference26 articles.
1. Synthesis of 4-substituted imino-4H-benzo[d][1,3] thiazin-2-amines via palladium-catalysed isocyanide insertion in 2-bromophenylthioureas
2. Palladium-Catalyzed Carbonylative Synthesis of Benzoxazinones from N-(o-Bromoaryl)amides Using Paraformaldehyde as the Carbonyl Source
3. A Convenient Palladium-Catalyzed Carbonylative Synthesis of 2-Aminbenzoxazinones from 2-Bromoanilines and Isocyanates
4. Room-Temperature Palladium-Catalyzed CH Activation:ortho-Carbonylation of Aniline Derivatives
5. Palladium-Catalyzed Synthesis of 2-Aminobenzoxazinones by Aerobic Oxidative Coupling of Anthranilic Acids and Isocyanides
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