Synthesis of 4-substituted imino-4H-benzo[d][1,3] thiazin-2-amines via palladium-catalysed isocyanide insertion in 2-bromophenylthioureas
Author:
Affiliation:
1. Medicinal & Process Chemistry Division
2. CSIR-Central Drug Research Institute
3. Lucknow-226031, India
4. Academy of Scientific and Innovative Research
5. New Delhi, India
Abstract
The palladium-catalysed isocyanide insertion in 2-bromophenylthioureas leads to the formation of 4-substituted imino-4H-benzo[d][1,3]thiazin-2-amines via C–S cross coupling reaction of the intermediate imidoylpalladium species.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA06875K
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