The squaramide-catalyzed asymmetric Michael/cyclization tandem reaction for the synthesis of chiral trifluoromethylated hydroxyimino tetrahydrobenzofuranones-Reference-Cited by-同舟云学术

The squaramide-catalyzed asymmetric Michael/cyclization tandem reaction for the synthesis of chiral trifluoromethylated hydroxyimino tetrahydrobenzofuranones

Published:2016 Issue:14 Volume:14 Page:3603-3607
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Liu Wei¹²³⁴⁵,Lai Xiaoyan¹²³⁴⁵,Zha Gaofeng¹²³⁴⁵,Xu Yan¹²³⁴⁵,Sun Panpan¹²³⁴⁵,Xia Tao¹²³⁴⁵,Shen Yongcun¹²³⁴⁵

Affiliation:

1. Department of Pharmacy

2. School of chemistry

3. Chemical Engineering and Life Sciences

4. Wuhan University of Technology

5. Wuhan 430070

Abstract

This paper presents efficient access to chiral hydroxyimino tetrahydrobenzofuranones featuring a trifluoromethyl group at an all-carbon quaternary stereocenter.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB00119J

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