Exploring the chelating capacity of 2-hydroxyphenyl-benzimidazole based hybrids with multi-target ability as anti-Alzheimer's agents-Reference-Cited by-同舟云学术

Exploring the chelating capacity of 2-hydroxyphenyl-benzimidazole based hybrids with multi-target ability as anti-Alzheimer's agents

Published:2018 Issue:20 Volume:42 Page:16503-16515
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Chaves Sílvia¹²³⁴⁵^ORCID,Hiremathad Asha¹²³⁴⁵^ORCID,Tomás Daniel¹²³⁴⁵^ORCID,Keri Rangappa S.⁶⁷⁸⁹¹⁰^ORCID,Piemontese Luca¹²³⁴⁵^ORCID,Santos M. Amélia¹²³⁴⁵^ORCID

Affiliation:

1. Centro de Química Estrutural

2. Instituto Superior Técnico

3. Universidade de Lisboa

4. 1049-001 Lisboa

5. Portugal

6. Centre for Nano and Material Sciences

7. Jain University

8. Jain Global Campus

9. Bangalore 562112

10. India

Abstract

Donepezil and tacrine hybrids, containing a 2-hydroxyphenyl-benzimidazole chelating moiety and with multifunctional anti-AD activity, are evaluated in terms of metal (Cu and Zn) chelating capacity.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C8NJ00117K

Reference50 articles.

1. Alzheimer's Disease

2. Drug Development Based on the Metals Hypothesis of Alzheimer's Disease

3. Alzheimer’s disease drug-development pipeline: few candidates, frequent failures