A general, versatile and divergent synthesis of selectively deuterated amines-Reference-Cited by-同舟云学术

A general, versatile and divergent synthesis of selectively deuterated amines

Published:2021 Issue:33 Volume:12 Page:11157-11165
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Lecomte Morgan¹,Lahboubi Mounsef¹,Thilmany Pierre¹,El Bouzakhi Adil¹,Evano Gwilherm¹^ORCID

Affiliation:

1. Laboratoire de Chimie Organique, Service de Chimie et PhysicoChimie Organiques, Université libre de Bruxelles (ULB), Avenue F. D. Roosevelt 50, CP160/06, 1050 Brussels, Belgium

Abstract

A general, versatile, divergent and metal-free synthesis of amines selectively deuterated at their α and/or β positions and relying on a simple treatment of ynamides with triflic acid and triethylsilane, either deuterated or not, is reported.

Funder

Fédération Wallonie-Bruxelles

Fonds De La Recherche Scientifique - FNRS

Université Libre de Bruxelles

Fonds pour la Formation à la Recherche dans l’Industrie et dans l’Agriculture

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC02622D

Reference91 articles.