Abietane diterpenoid of Salvia sahendica Boiss and Buhse potently inhibits MCF-7 breast carcinoma cells by suppression of the PI3K/AKT pathway-Reference-Cited by-同舟云学术

Abietane diterpenoid of Salvia sahendica Boiss and Buhse potently inhibits MCF-7 breast carcinoma cells by suppression of the PI3K/AKT pathway

Published:2015 Issue:23 Volume:5 Page:18041-18050
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kafil Vala¹²³⁴⁵,Eskandani Morteza¹²³⁴⁵,Omidi Yadollah¹²³⁴⁶,Nazemiyeh Hossein¹²³⁴⁶,Barar Jaleh¹²³⁴⁶

Affiliation:

1. Research Center for Pharmaceutical Nanotechnology

2. Tabriz University of Medical Sciences

3. Tabriz

4. Iran

5. Student Research Committee

6. Faculty of Pharmacy

Abstract

Ketoethiopinone and ortho-diacetate aethiopinone were identified from the roots of S. sahendica and evaluated for their anti-cancer activity in MCF-7 breast cell lines. The type of cell death and the mechanism by which MCF-7 proliferation was limited were investigated.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA14905J

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