Metal- and base-free synthesis of functionalized α,α-difluoroimines via electrophilic fluorination of N-substituted enamines-Reference-Cited by-同舟云学术

Metal- and base-free synthesis of functionalized α,α-difluoroimines via electrophilic fluorination of N-substituted enamines

Published:2018 Issue:38 Volume:16 Page:6895-6899
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Li Fangyi¹²³⁴^ORCID,Qiu Changfu¹²³⁴^ORCID,Yin Guangwei¹²³⁴,Wang Chunhua¹²³⁴^ORCID,Li Zheng¹²³⁴^ORCID

Affiliation:

1. College of Pharmaceutical Engineering of Traditional Chinese Medicine

2. Tianjin University of Traditional Chinese Medicine

3. Tianjin 300193

4. China

Abstract

A metal- and base-free synthesis of functionalized α,α-difluoroimines is presented. The reaction features mild condition, high E/Z control and broad functional group tolerance. The utility of the products was demonstrated through valuable synthetic transformations.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01941J

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