Specific dsDNA recognition by a mimic of the DNA binding domain of the c-Myc/Max transcription factor-Reference-Cited by-同舟云学术

Specific dsDNA recognition by a mimic of the DNA binding domain of the c-Myc/Max transcription factor

Published:2017 Issue:49 Volume:53 Page:6653-6656
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Ruiz García Yara¹²³⁴⁵,Pabon-Martinez Y. Vladimir⁶⁷⁸⁹¹⁰^ORCID,Smith C. I. Edvard⁶⁷⁸⁹¹⁰^ORCID,Madder Annemieke¹²³⁴⁵^ORCID

Affiliation:

1. Organic and Biomimetic Chemistry Research Group

2. Department of Organic and Macromolecular Chemistry

3. Ghent University

4. Gent

5. Belgium

6. Clinical Research Center

7. Department of Laboratory Medicine

8. Karolinska Institutet

9. Karolinska University Hospital Huddinge

10. Stockholm

Abstract

We here report on the synthesis of the first mimic of the DNA binding domain of the c-Myc/Max-bHLH-ZIP transcription factor able to selectively recognize its cognate E-box sequence 5′-CACGTG-3′ through the major groove of the double-stranded DNA.

Funder

Vetenskapsrådet

Fonds Wetenschappelijk Onderzoek

Bijzonder Onderzoeksfonds

H2020 Marie Skłodowska-Curie Actions

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/CC/C7CC01705G

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