A cascade reaction of indolyl-migratory isocyanide insertion, scaffold rearrangement and redox-neutral event with isocyanide as a C<sub>(sp<sup>3</sup>)</sub>H–N synthon efficiently constructs indolylisoindolinones-Reference-Cited by-同舟云学术

A cascade reaction of indolyl-migratory isocyanide insertion, scaffold rearrangement and redox-neutral event with isocyanide as a C_(sp³)H–N synthon efficiently constructs indolylisoindolinones

Published:2022 Issue:84 Volume:58 Page:11827-11830
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Sisodiya Shailendra¹,Acharya Ayan¹^ORCID,Nagpure Mithilesh¹^ORCID,Roy Nibedita¹^ORCID,Giri Santosh K.¹^ORCID,Yadav Hare Ram²,R. Choudhury Angshuman²^ORCID,Guchhait Sankar K.¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Mohali, Punjab 160062, India

2. Department of Chemistry, Indian Institute of Science Education and Research, Mohali, Sector 81, S.A.S. Nagar, Manauli PO, Mohali, Punjab 140306, India

Abstract

Herein, we report a Pd(0)-catalyzed cascade reaction with multifunction of isocyanide as a nucleophile promoter for rearrangement and a hydride source.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D2CC04273H

Reference43 articles.

1. Multicomponent Reactions with Isocyanides

2. Recent Developments in the Isonitrile‐Based Multicomponent Synthesis of Heterocycles

3. Recent Developments in Isocyanide Based Multicomponent Reactions in Applied Chemistry

4. Tandem Radical Reactions of Carbon Monoxide, Isonitriles, and Other Reagent Equivalents of the Geminal Radical Acceptor/Radical Precursor Synthon

5. Palladium-Catalyzed Migratory Insertion of Isocyanides: An Emerging Platform in Cross-Coupling Chemistry

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis of N-fused polycyclic indoles via a Pd-catalyzed multicomponent cascade reaction consisting of an amide-directed [3+1+1] annulation reaction of 3-diazo oxindole and isocyanides;New Journal of Chemistry;2024

2. Rapid Access to Fused Tetracyclic N-Heterocycles via Amino-to-Alkyl 1,5-Palladium Migration Coupled with Intramolecular C(sp³)–C(sp²) Coupling;Organic Letters;2023-08-21

3. Palladium-Catalyzed Tandem C(sp³)-H Insertion Cyclization of 2-(2-Vinylarene)acetonitriles with Isocyanides to Access Naphthalen-2-amines;The Journal of Organic Chemistry;2023-08-14

4. Total Syntheses of Iheyamines A and B;J ORG CHEM;2023

5. Total Syntheses of Iheyamines A and B;The Journal of Organic Chemistry;2022-12-29