Synthesis of N-fused polycyclic indoles via a Pd-catalyzed multicomponent cascade reaction consisting of an amide-directed [3+1+1] annulation reaction of 3-diazo oxindole and isocyanides

Author:

Soam Pooja1,Mandal Debasish12ORCID,Tyagi Vikas12ORCID

Affiliation:

1. School of Chemistry and Biochemistry, Thapar Institute of Engineering and Technology, Patiala-147004, Punjab, India

2. Centre of Excellence for Emerging Materials, Thapar Institute of Engineering and Technology, Patiala-147004, Punjab, India

Abstract

A palladium-catalyzed and amide-assisted multicomponent reaction of 3-diazo oxindole, isocyanide, and water to generate biologically important oxazole-fused indole scaffolds has been reported.

Funder

Science and Engineering Research Board

Department of Science and Technology, Ministry of Science and Technology, India

Thapar Institute of Engineering and Technology

Publisher

Royal Society of Chemistry (RSC)

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