Efficient conversion of spent mushroom substrate into a high value-added anticancer drug pentostatin with engineered Cordyceps militaris-Reference-Cited by-同舟云学术

Efficient conversion of spent mushroom substrate into a high value-added anticancer drug pentostatin with engineered Cordyceps militaris

Published:2021 Issue:24 Volume:23 Page:10030-10038
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Zou Gen¹^ORCID,Li Bo¹²,Wang Ying¹,Yin Xin¹²,Gong Ming¹,Shang Junjun¹,Wei Yongjun³^ORCID,Li Xiaoling²⁴,Bao Dapeng¹

Affiliation:

1. Shanghai Key Laboratory of Agricultural Genetics and Breeding; Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, 1000 Jinqi Rd, 201403, Shanghai, China

2. School of Chemistry and Life Science, Changchun University of Technology, 2055 Yan ‘an Avenue, Chaoyang District, Changchun, 130012, Jilin, China

3. Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Laboratory of Synthetic Biology, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450051, PR China

4. School of Chemical Engineering and Resource Recycling, Wuzhou University, 3 Fumin Avenue, Wanxiu District, Wuzhou, 543002, Guangxi, China

Abstract

An engineered Cordyceps militaris cell factory enables sustainable disposal of spent mushroom substrate while synthesizing valuable anticancer drug.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/GC/D1GC03594K

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